Edition V19N04 | Year 2014 | Editorial Evidence based Orthodontics | Pages 27 to 29
Sample size calculation is part of the early stages of conducting an epidemiological, clinical or lab study. In preparing a scientific paper, there are ethical and methodological indications for its use. Two investigations conducted with the same methodology and achieving equivalent results, but different only in terms of sample size, may point the researcher in different directions when it comes to making clinical decisions. Therefore, ideally, samples should not be small and, contrary to what one might think, should not be excessive. The aim of this paper is to discuss in clinical language the main implications of the sample size when interpreting a study.
Sample calculation, Sample size, Clinical trial, Methodology, Scientific evidence,
Faber J, Fonseca LM. How sample size inluences research outcomes. Dental Press J Orthod. 2014 July-Aug;19(4):27-9. DOI: http://dx.doi. org/10.1590/2176-9451.19.4.027-029.ebo